Pharmaceutical composition containing carbachol and other cholin

Details Pharmaceutical composition containing carbachol and other cholin Pharmaceutical composition containing carbachol and other cholin

1994-10-20

1997-10-21

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514912, A61K 3114

Patent

active

056797133

ABSTRACT:
The present invention relates to the use of carbachol and other cholinergic substances for the treatment of keratoconjunctivitis sicca.

REFERENCES:
patent: 2185220 (1940-01-01), Nabenhauer
patent: 4804539 (1989-02-01), Guo et al.
The Merck Index, Eleventh Edition, 1984, p. 268.
Victor F. Smolen et al., "Biophasic Availability of Ophthalmic Cabachol I: Mechanisms of Cationic Polymer-and Surfactant-Promoted Miotic Activity", J. Pharm. Sciences 62, 1973 (958-61).
Verinder S. Nirankari et al., "Ocular Manifestations of Shy-Drager Syndrome", Ann. Ophthalmol. (USA), 1982, 14/7 (635-38).
Han H. Stolze et al., "Influence of secretagogues on volume and protein pattern in rabbit lacrimal fluid", Curr Eye Res, (1985 Apr.) 4(4) 489-92.
"Dorland's Illustrated Medical Dictionary, 26th Ed.", 1985, W.B. Saunders Company, see p. 110 arecoline and see p. 217 carbachol.
Susan Budavari et al. "The Merck Index, eleventh edition", 1989, Merck & Co., Inc., USA, see p. 935 No. 5847, Methanol Chloride and see p. 185 No. 1207, Bethanechol Chloride.
Goodman and Gilman's "The Pharmacological Basis of Therapeutics" (Eighth's Ed) Chap. 6, pp. 126-127.
Meyler's Side Effects of Drugs Eleventh Ed. (Mng Dukes, ed) Elsevier 1988, Ch. 49, p. 991.

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