Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1993-08-12
1994-10-25
Rose, Shep
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514769, 514772, A61K 31135
Patent
active
053589700
ABSTRACT:
This application discloses a method of inhibiting degradation of the antidepressant bupropion hydrochloride in a solid pharmaceutical formulation, so that the pharmaceutical formulation will maintain at least 80% of its initial bupropion potency after one year.
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Laizure et al. Ther. Drug Monit. 7(y):447-458 1985 "Stability of Bupropion" GA. 10y: 814822 (1985).
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Kalidindi Sanyasi R.
Ruff Michael D.
Sutton, Jr. Joel E.
Brown Donald
Burroughs Wellcome Co.
Eberhardt Wayne R.
Nielsen Lawrence A.
Rose Shep
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