Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1990-05-14
1992-02-25
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424452, 424456, 424457, 424461, 424462, 424460, 424469, 424470, 424473, 424493, 424494, 424495, 424496, 424497, 424501, 424DIG7, 424 7812, 514824, A61K 918, A61K 924, A61K 916, A61K 31785
Patent
active
050911759
ABSTRACT:
A pharmaceutical composition useful for treating hypercholesterolemia comprising a bile acid sequestrant resin such as cholestyramine and cholestipol maintained in a semipermeable water-insoluble material; wherein said semipermeable material enables bile acids from the digest tract to contact and bind to said resin while preventing substances having a higher molecular weight than bile acids from contacting said resin material. A method for treating hypercholesterolemia using the inventive composition is also disclosed.
REFERENCES:
patent: 3974272 (1976-08-01), Polli et al.
patent: 4362711 (1982-12-01), Cerami
patent: 4747881 (1988-05-01), Shaw et al.
patent: 4902501 (1990-02-01), Bandi et al.
Publication titled "Sampling Intestinal Content with a Sequestering Capsule", Mayo Clin Proc, Mar. 1976, vol. 51 by Neville E. Hoffman et al.
Hagerman Larry M.
Imondi Anthony R.
Erbamont Inc.
Page Thurman K.
Webman E. J.
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