Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Bacterium or component thereof or substance produced by said...
Patent
1976-02-27
1977-11-01
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Bacterium or component thereof or substance produced by said...
A61K 3134
Patent
active
040566269
ABSTRACT:
A pharmaceutical composition containing as the essential active ingredient a benzofuran derivative of the formula: ##STR1## wherein A is --COR', ##STR2## or ethyl group; B is hydrogen atom when A is --COR' ##STR3## or --COR" substituted at the 3 or 4 position of the benzofuran nucleus when A is ethyl; R is an alkyl group having 1 to 5 carbon atoms; R' is an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 3 carbon atoms or phenyl group; R" is an alkyl group having 1 to 4 carbon atoms, phenyl or phenylalkyl group wherein the alkyl moiety has 1 to 2 carbon atoms; and the substituted propoxy group is at the 3, 4, 5, 6 or 7 position of the benzofuran nucleus; or a pharmaceutically acceptable acid addition salt thereof in admixture with a pharmaceutically acceptable carrier. The pharmaceutical composition possesses a superior .beta.-adrenergic blocking activity and local anesthetic activity, and is useful for the prevention and treatment of heart diseases, hypertension and hyperthyroidism.
REFERENCES:
patent: 3590084 (1971-06-01), Peperkamp et al.
Ikemoto Masahiko
Ito Kiyoshi
Kimura Kazuhiko
Nakanishi Teruo
Kakenyaku Kako Co., Ltd.
Waddell Frederick E.
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