Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1986-08-22
1989-04-11
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
435 68, 435911, A61K 3702, A61K 3570
Patent
active
048206890
ABSTRACT:
Disclosed herein is a pharmaceutical composition having antirheumatic activity, antithrombotic activity, analgetic activity, antipyretic activity, anti-hyperlipemic activity and anti-inflammatory activity and activities of reducing the level of blood sugar, raising the coronary blood flow, improving the capability of deformation of erythrocytes, reducing the blood pressure, ameliorating proteinuria and proteinemia and regulating production or metabolism of prostaglandins in a mammal in dosage unit form, which comprises a dosage effective to produce said activities of a glycoprotein having a molecular weight of 5000 to 300000 as determined by ultracentrifugal method and about 18 to 38% by weight of proteins, produced by culturing a basidiomycetous fungal species belonging to the genus Coriolus, extracting the thus proliferated mycelia or fruit bodies with hot water or aqueous alkali solution and removing low molecular weight substances having a molecular weight of less than 5000 from the extract.
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Kureha Chemical Industry Co., Ltd., "Outline of PSK", 1977, pp. 28-30.
Fujii Takayoshi
Furusho Takao
Ikuzawa Masanori
Matsunaga Ken-ichi
Oguchi Yoshiharu
Brown Johnnie R.
Kureha Kagaku Kogyo Kabushiki Kaisha
Stone Jacqueline M.
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