Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1988-12-16
1991-04-16
Stone, Jacqueline
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
435 711, 435911, A61K 3702
Patent
active
050082434
ABSTRACT:
Disclosed herein is a pharmaceutical composition having antirheumatic activity, antithrombotic activity, analgetic activity, antipyretics activity, anti-hyperlipemic activity and anti-inflammatory activity and activities of reducing the level of blood sugar, raising the coronary blood flow, improving the capability of deformation of erythrocytes, reducing the blood pressure, ameliorating proteinuria and proteinemia and regulating production or metabolism of prostaglandins in a mammal in dosage unit form, which comprises a dosage effective to produce said activities of a glycoprotein having a molecular weight of 5000 to 300,000 as determined by ultracentrifugal method and about 18 to 38% by weight of proteins, produced by culturing a basidiomycetous fungal species belonging to the genus Coriolus, extracting the thus proliferated mycelia or fruit bodies with hot water or aqueous alkali solution and removing low molecular weight substances having a molecular weight of less than 5000 from the extract.
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Fujii Takayoshi
Furusho Takao
Ikuzawa Masanori
Matsunaga Ken-ichi
Oguchi Yoshiharu
Kureha Kagaku Kogyo Kabushiki Kaisha
Stone Jacqueline
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