Pharmaceutical composition containing a drug/.beta.-cyclodextrin

Details Pharmaceutical composition containing a drug/.beta.-cyclodextrin Pharmaceutical composition containing a drug/.beta.-cyclodextrin

1997-04-09

1999-02-02

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424489, A61K 914, A61K 916, A61K 946

Patent

active

058661620

ABSTRACT:
A pharmaceutical composition for oral consumption in liquid form is provided, characterized in that the composition contains a drug, preferably a lipophilic NSAID, complexed to .beta.-cyclodextrin in a formulation also containing an acid-base couple, preferably an effervescent acid-base couple. The weight of the acid-base couple is greater than 1% of the weight of water in which the composition is to be dissolved, and provides an acid or neutral pH.

REFERENCES:
patent: 4762702 (1988-08-01), Gergely et al.
patent: 5019563 (1991-05-01), Hunten et al.
patent: 5024997 (1991-06-01), Motola et al.
patent: 5037657 (1991-08-01), Jones et al.

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