Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-11-21
1990-11-20
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544360, A61K 31495, C07D40104
Patent
active
049719696
ABSTRACT:
Pharmaceutical composition which is useful as a medicinal product, in particular for the treatment of disorders of the central nervous system, characterized in that it contains customary pharmaceutical excipients, and at least one of the compounds of formula ##STR1## in which the trifluoromethyl substituent is at the 4-position, at the 5-position, or at 4- and 5-positions of the pyridinyl ring, and the substituent R denotes either hydrogen or a halogen, such as chlorine, at position(s) of the pyridinyl ring not occupied by CF.sub.3, and its pharmaceutically acceptable salts.
REFERENCES:
patent: 4876256 (1989-10-01), Coss et al.
Saari et al., J. Med. Chem. 1983, 26, 1696-1701.
Abou-Gharbia, Chem. Abst. 107-217647d, eq. EP 220873 cited in the specification.
Lavielle et al., Chem. Abst 110-75296z (1989) eq. EP 282390 cited in the specification.
Carlier Patrick
Monteil Andre
Poisson Claude
Akzo N.V.
Blackstone William M.
Shen Cecilia
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