Pharmaceutical composition containing 1,1,3,5-substituted biuret

Details Pharmaceutical composition containing 1,1,3,5-substituted biuret Pharmaceutical composition containing 1,1,3,5-substituted biuret

1981-04-24

1983-02-01

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 3117

Patent

active

043715443

ABSTRACT:
An analgesic, anti-inflammatory or anti-pyretic composition containing 1,1,3,5-substituted biuret compound of the formula, ##STR1## wherein R.sup.1 is a lower alkyl group or a phenyl group; R.sup.2 is a lower alkyl group, a phenyl group or a substituted phenyl group having chlorine atom(s), methyl group(s) or methoxy group(s) as the substituent(s), further R.sup.1 and R.sup.2 may form a single ring containing one or two hetero atoms including the adjacent nitrogen atom; R.sup.3 is a hydrogen atom, a lower alkyl group or a phenyl group; R.sup.4 is a phenyl group, a substituted phenyl group having halogen atom(s), trifluoromethyl group(s), methyl group(s), methoxy group(s), dimethyl-amino group(s), nitro group(s), hydroxyl group(s), acetyl group(s), or methylthio group(s) as the substituent(s), a benzyl group, a cyclohexyl group or a lower alkyl group, as the active ingredient.

REFERENCES:
J.A.C.S., Jun. (1940) 1595-1596.
Chem. Abst., 94: 102866V (1981) referring to German Offen No. 3,012,124.
Chem. Abst. 9th Coll. Index Chem. Substances Hexanone-Iron p. 19527CS.

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