Pharmaceutical composition comprising squalene epoxidase...

Details Pharmaceutical composition comprising squalene epoxidase... Pharmaceutical composition comprising squalene epoxidase...

2005-07-19

2005-07-19

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S028000, C514S029000, C514S030000, C514S031000, C514S649000, C514S650000, C514S655000, C536S007100, C536S007200, C564S387000

Reexamination Certificate

active

06919317

ABSTRACT:
Synergistic combinations of a squalene epoxidase inhibitor such as terbinafine and a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro, 33-desoxyascomycin are provided, which are useful in particular in the treatment of diseases involving fungal or suspected fungal infection, for immunomodulation or immunosuppression in conditions in which fungal or suspected fungal colonisation of e.g. the skin plays a role, such as atopic dermatitis and seborrhoeic dermatitis, and in situations of fungal resistance.

REFERENCES:
patent: 5985906 (1999-11-01), Meingassner et al.
patent: 2001/0003589 (2001-06-01), Neuer et al.
patent: 0427680 (1991-05-01), None
patent: 0515310 (1992-11-01), None

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