Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2005-05-31
2005-05-31
Barts, Samuel (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C514S553000, C514S646000, C562S115000, C562S114000, C562S030000, C564S394000, C564S442000
Reexamination Certificate
active
06900245
ABSTRACT:
The present invention relates to a pharmaceutical composition for treating or preventing obesity, comprising novel crystalline sibutramine methanesulfonate hemihydrate of formula (I). The crystalline sibutramine methanesulfonate hemihydrate according to the present invention has a much higher solubility in water, and enhanced stability under a high humidity/temperature condition, as compared with sibutramine hydrochloride monohydrate
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Chang Young-Kil
Kim Han-Kyong
Lee Gwan-Sun
Lee Jae-Cheol
Lee Jae-Heon
Anderson Kill & Olick PC
Barts Samuel
Hanmi Pharm. Co. Ltd.
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