Pharmaceutical composition comprising a spiro oxathiolon/quinucl

Details Pharmaceutical composition comprising a spiro oxathiolon/quinucl Pharmaceutical composition comprising a spiro oxathiolon/quinucl

1990-10-19

1992-04-21

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514278, 514 78, 514 11, A01N 3718, A01N 4342, A01N 5726, A61K 3700

Patent

active

051068311

ABSTRACT:
A pharmaceutical composition is disclosed comprising (-)-cis-2-methylspiro(1,3-oxathiolan-5,3')quinuclidine, and/or the pharmaceutically compatible acid addition salts thereof, together with at least one of physostigmine, tetrahydroaminoacridine, choline, lecithin, piracetam, aniracetam, pramiracetam, oxiracetam, 4-aminopyridine, 3,4-diaminopyridine, somatostatin, pirenzepine, N-methylatropine, N-butylscopolamine, scopolamine, clonidine, quanfamicine and Nerve Growth Factor. Also disclosed is a method for treating senile dementia of Alzheimer's type, which comprises coadministering to a patient in need thereof an effective dose of the spiro compound together with at least one other compound selected from those listed above.

REFERENCES:
patent: 4855290 (1989-08-01), Fisher

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