Pharmaceutical composition comprising 5,6-dihydrodibenzo[A,G] Qu

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514284, 514824, A61K 3144

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active

060309792

ABSTRACT:
The present invention provides a pharmaceutical composition comprising 5,6-dihydrodibenzo[a,g]quinolizinium derivative and the salts thereof of formula (I) which specifically inhibits the sterol 14-reductase which is involved in the distal pathway of cholesterol biosynthesis, and the use of the compound of formula (I) for treating hypercholesterolaemia or hyperlipidaemia. ##STR1##

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Naruto et al., Tetrahedron Lett., vol. 19, p. 1597-1600 (1976).
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