Pharmaceutical composition and process for isolation of...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...

Reexamination Certificate

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Reexamination Certificate

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07118766

ABSTRACT:
The present invention relates to a pharmaceutical composition comprising a bioactive constituent trans-tetracos-15-enoic acid and a process for the isolation of tetracos-15-enoic acid from the plantIndigofera tinctoriaalong with a method of treatment for hepatotoxicity.

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patent: WO 99/11223 (1999-03-01), None
Anand, K.K., et al., “Protective Effect of Alcoholic Extract of Indigofera tinctoria Linn. In Experimental Liver Injury”, Indian Journal of Experimental Biology, vol. 17, pp. 685-687, (1979).
Anand, K.K., et. al., “Histological Evidence of Protection by Indigofera tinctoria Linn. Against Carbontetracholoride Induced Hepatotoxicity—An Experimental Study”, Indian Journal of Experimental Biology, vol. 19, pp. 208-300, (1981).
Chopra, R.N., et al., Glossary of Indian Medicinal Plants, Council of Scientific & Industrial Research New Delhi, p. 141 (1956).
Curtius, H. Ch., et al., “Glycogen and Enzymes of Glycogen Metabolism”, Clinical Biochemistry Principles and Methods, vol. II, pp. 1208-1235, (1974).
Lowry, Oliver H., et al., “Protein Measurement with the Folin Phenol Reagent”, The Journal of Biological Chemistry, vol. 193, pp. 265-275 (1951).
Nadkarni, K.M., Indian Materia Medica, vol. 1, p. 680, (1954).
Szasz, Gabor, “Reaction-Rate Method for γ-Glutamyltransferase Activity in Serum”, Clinical Chemistry, vol. 22, No. 12, pp. 2051-2055.

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