Pharmaceutical composition and method of treatment or prophylaxi

Details Pharmaceutical composition and method of treatment or prophylaxi Pharmaceutical composition and method of treatment or prophylaxi

1989-11-16

1991-05-21

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514821, A61K 3124

Patent

active

050176099

ABSTRACT:
A pharmaceutical composition is disclosed, which contains a short-acting .beta.-blocking compound of the formula ##STR1## wherein R.sub.1 may be an alkyl, cycloalkyl, alkenyl, alkynyl, alkyl carboxymethyl, aryl carboxymethyl, aryl or aralkyl, A may be an alkylene or alkenylene, X may be independently amino, hydrogen, halogen, hydroxy, alkoxy, aryloxy, aralkyl, cyano, amido or trifluoromethyl, n is an integer from 1 to about 4, R may be an alkyl, propargyl, dimethylpropargyl or hydroxyalkyl; or a pharmaceutically acceptable salt thereof in a hydroalcoholic solution further containing a physiologically acceptable buffering agent, ethanol and a physiologically acceptable liquid polyhydric compound. A method for treatment or prophylaxis of cardiac disorders using the composition of the present invention is also disclosed.

REFERENCES:
patent: 3742023 (1973-06-01), Koppe et al.
patent: 3872147 (1975-03-01), Koppe et al.
patent: 4146630 (1979-03-01), Kampe et al.
patent: 4191765 (1980-03-01), Fritsch et al.
patent: 4346093 (1982-08-01), Friebe et al.
patent: 4387103 (1983-06-01), Erhardt et al.
patent: 4829086 (1989-05-01), Bodor
Remington's Pharmaceutical Sciences, 16th ed. (1980), pp. 214, 238, 1253-1256 and 1463-1468.
Morrison and Boyd, Organic Chemistry, 3rd Edition, Sec. 20.16, p. 675.
L. H. Smith, Journal of Applied Chemistry and Biotechnology, 28(3):201-212 (1978).
Hisashi Nogami et al., Chemical and Pharmaceutical Bulletin, vol. 10, pp. 1158-1160 (1962).
Joseph M. Talmage et al., Journal of Pharmaceutical Sciences, vol. 57, No. 6, pp. 1073-1074 (Jun. 1968).
Pharmaceuticals, vol. 66, p. 6499, 68878k (1967).
H. A. Garrera et al., Rev. Latinoamer, Quim., 7:4-8 (1976).
P. B. Sheth et al., Journal of Pharmaceutical Sciences, vol. 56, No. 8, pp. 983-986 (Aug. 1967).
M. Balakrishnan et al., Tetrahedron Letters, No. 45, pp. 4617-4620 (1972).
H. A. Garrera et al., Rev. Latinoamer, Quim., 5:201-205 (1974).

Affiliated with

Also associated with

Rating

Pharmaceutical composition and method of treatment or prophylaxi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical composition and method of treatment or prophylaxi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition and method of treatment or prophylaxi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-238933