Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1989-06-02
1991-04-30
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514315, 514934, A61K 3170, A61K 31445
Patent
active
050118293
ABSTRACT:
A pharmaceutical composition and a method of inhibiting human immunodeficiency virus (HIV) is disclosed which comprises administering to an HIV infected patient a synergistic combination of 3'-azido-3'-deoxythymidine (AZT) and N-butyl deoxynojirimycin (N-butyl DNJ) in an amount which achieves antiviral efficacy.
REFERENCES:
patent: 4724232 (1988-02-01), Rideout et al.
patent: 4849430 (1989-07-01), Fleet et al.
patent: 4857511 (1989-08-01), Rideout et al.
Pollner, Medical World News, Dec. 11, 1989, p. 53.
Johnson et al., Antimicrobial, Agents & Chemother, 33, 53-57 (1989).
Hartshorn et al., Antimicrobiol. Agents & Chemother. 31, 168-172 (1987).
Hirsch & Kaplan, Antimicrobiol. Agents & Chemother. 31, 839-843 (1987).
Johnson et al., IV Inter. Conf. Aids, Jun. 12-16, 1988, Stockholm, Sweden.
Johnson et al., J. Infect. Diseases 159, 837-844 (1989).
Spector et al., Infect. Diseases 159, 822-828 (1989).
Fleet et al., Febs Lett. 237, 128-132 (1988).
Karpas et al., Proc. Natl. Acad. Sci. U.S.A. 85, 9229-9233 (1988).
Walker et al., Proc. Natl. Acad. Sci. U.S.A. 84, 8120-8124 (1987).
Poli et al., Science 244, 575-577 (1989).
Anon., Science 244, 511 (1989).
Hirsch and Kaplan, Scie. Amer. 256, 76-85 (1987).
Hirsch Martin S.
Johnson Victoria A.
G. D. Searle & Co.
Goldberg Jerome D.
Matukaitis Paul D.
Meyer Scott J.
Williams, Jr. James W.
LandOfFree
Pharmaceutical composition and method of inhibiting virus does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical composition and method of inhibiting virus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition and method of inhibiting virus will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-640489