Pharmaceutical composition and method for the treatment of colit

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ortho-hydroxybenzoic acid or derivative doai

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A61K 3160

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active

050414313

ABSTRACT:
A pharmaceutical composition containing as active ingredient 5-aminosalicyclic acid or a pharmaceutically acceptable salt or ester thereof allow the treatment of colitis ulcerosa or Crohn's disease by oral administration. A particular slow-release tablet formation and its preparation is disclosed.

REFERENCES:
patent: 2805977 (1957-09-01), Robinson et al.
patent: 2928770 (1960-03-01), Bardami
patent: 2987445 (1961-06-01), Levesque
patent: 3080294 (1963-03-01), Eberperd
patent: 3081233 (1963-03-01), Enz et al.
patent: 3108046 (1963-10-01), Harbit
patent: 3131123 (1964-04-01), Masquelier
patent: 3133863 (1964-05-01), Tansey
patent: 3143472 (1964-08-01), Lappas et al.
patent: 3388041 (1968-06-01), Gaus et al.
patent: 3431338 (1969-03-01), Munzel
patent: 3784683 (1974-01-01), Prillig et al.
patent: 3906086 (1975-09-01), Guy et al.
patent: 3950521 (1976-04-01), Higuchi et al.
patent: 4066756 (1978-01-01), Orr et al.
patent: 4190716 (1980-02-01), Parkinson et al.
patent: 4193985 (1980-03-01), Bechgaard et al.
patent: 4211777 (1980-07-01), Chambers
patent: 4221810 (1980-09-01), Tahara et al.
patent: 4298595 (1981-11-01), Parkinson et al.
patent: 4350689 (1982-09-01), Sloboda
patent: 4440754 (1984-04-01), Sorenson
patent: 4440763 (1984-04-01), Lover
patent: 4440765 (1984-04-01), Diamond et al.
patent: 4455305 (1984-06-01), Rokos
patent: 4476553 (1985-01-01), Halskov
patent: 4539198 (1985-09-01), Powell et al.
patent: 4540685 (1985-09-01), Bauer
patent: 4559330 (1985-12-01), Agback et al.
patent: 4591584 (1986-05-01), Agback
patent: 4632921 (1986-12-01), Bauer
patent: 4699902 (1987-10-01), Bauer
Pieniaszek, Jr. et al., Journal of Pharmaceutical Sciences, vol. 68, No. 10, Oct. 1979, pp. 1323-1325.
Beilsteins Handbuch der Organischen Chemie, 4th Edition, Julius Springen Verlag (Berlin 1931), vol. XLV, p. 583.
Merck Index, Ninth Edition, pp. 66-67 (1976).
Goodman et al., "Ulcerative Colitis", Clinical Gastroenterology, 1978, pp. 3-16, 25, 73-74, 109-124, 128.
Kirsner, JAMA, Feb. 8, 1980, vol. 243, No. 6.
Khan et al., "An Experiment to Determine the Active Therapeutic Moiety of Sulphasalazine", Lancet 2, Oct. 29, 1977, pp. 892-895.
Peppercorn et al., Gastroenterology, vol. 64, No. 2, 1973, pp. 240-245.
Willoughby et al., Scand J. Gastroent. 1980, 15, pp. 715-719.
Fischer et al., J. Chromatography, 162 (1979), pp. 237-243.
van Hees et al., Lancet, 1, 1978, p. 277.
van Hees et al., Gut, 1979, 20, pp. 300-304.
Schroder et al., Clin. Pharm. and Ther., vol. 13, No. 4, 1972.
Klotz et al., New Engl. J. of Med., 303, No. 26, Dec. 25, 1980, pp. 1499-1502.
Binder et al., "Disodium Cromoglycate in the Treatment of Ulcerative Colitis and Crohn's Disease", Gut, vol. 22, 1981, pp. 55-60.
Shafii et al., "Absorption, Enterohepatic Circulation, and Excretion of 5-Aminosalicyclic Acid in Rates", Gastroenterology, vol. 77, No. 5, 1982, pp. 297-299.
Rasmussen et al., "Treatment of Crohn's Disease with Peroral 5-Amino-Salicyclic Acid", Gastroenterology, 1983, vol. 85, pp. 1350-1353.
Heatley et al., "Disodium Cromoglycate in the Treatment of Chronic Proctitis", Gut, 1975, 16, pp. 559-563.
Mani et al., "Treatment of Ulcerative Colitis with Oral Disodium Cromo-Glycate", The Lancet, Feb. 28, 1976, pp. 439-441.
Dronfield et al., "Comparative Trial of Sulphasalazine and Oral"Sodium Cromoglycate in the Maintenance or Remission in Ulcerative Colitis, Gut, 1978, 19, pp. 1136-1139.
Willoughby et al., "Comparison of Disodium Cromoglycate and Sulpha-Salazine as Maintenance Therapy for Ulcerative Colitis", The Lancet, Jan. 20, 1979, pp. 119-122.
Kakemi, Chem. Abst., vol. 67, #115435W (1967).
Vavilin, Chem Abst., vol. 77, #49594a (1972).
Buckell, "Controlled Trial of Disodium Cromoglycate in Chronic Persistent Ulcerative Colitis", Gut, 1978, 19, pp. 1140-1143.
Wagner, Chem. Abst., vol. 79, #45733p, (1973).
Badawi, Chem. Abst., vol. 94, #127217x, (1981).
Campieri et al., "A Double-Blind Clinical Trial to Compare the Effects of 4-Aminosalicylic Acid to 5-Aminosalicylic Acid in Topical Treatment of Ulcerative Colitis", Digestion, 29, 1984, pp. 204-208.
Selby et al., "Topical Treatment of Distal Ulcerative Colitis with 4-Aminosalicylic Acid Enemas", Digestion, 29, 1984, pp. 231-234.
Gandolfo et al., "Treatment of Distal Colitis with 4-ASA Enemas", Abstracts of Papers 1391, Gastroenterology, vol. 88, No. 5, Part 2.
Campieri, "Topical Treatment of Ulcerative Colitis with 5-Aminosalicylic Acid (5-ASA) and 4-Aminosalicylic Acid (4-ASA) Enemas".
Gandolfo, J. et al., "4-Aminosalicylic Acid Retention Enemas in Treatment of Distal Colitis", Digestive Diseases and Sciences, vol. 32, No. 7, Jul. 1987, pp. 700-704.
Walt, R. et al., "Colitis Associated with Non-Steroidal Anti-Inflammatory Drugs", British Medical Journal, vol. 288, Jan. 21, 1984, p. 238.
Gilat, T. et al., "Prostaglandins and Ulcerative Colitis", Gastroenterology, May 1979, p. 1083.
Campieri, M. et al., "Prostaglandins Indomethacin and Ulcerative Colitis", Gastroenterology, Jan. 1980, p. 193.
Gould, S. et al., "Studies of Prostaglandins and Sulphasalazine in Ulcerative Colitis", Prostaglandins and Medicine, 6, 1981, pp. 165-182.
Rampton, D. et al., "Prostaglandin Synthesis Inhibitors in Ulcerative Colitis: Flurbiprofen Compared with Conventional Treatment", Prostaglandins, vol. 21, No. 3, Mar. 1981, pp. 417-425.
Rampton, D. et al., "Relapse of Ulcerative Proctocolitis During Treatment with Non-Steroidal Anti-Inflammatory Drugs", Postgraduate Medical Journal, No. 57, May 1981, pp. 297-299.
Badawi, A. et al., "Drug Release from Matrices Made of Polymers with Reacting Sites", International Journal of Pharmaceutics, 6, 1980, pp. 55-62.
Goldman et al., Gastroenterology, vol. 65, No. 1, 1973, pp. 166-169.
Goldman et al., The New England Journal of Medicine, vol. 293, No. 1, pp. 20-23.
Physician's Desk Reference, p. 1302, copyright 1969.
Physician's Desk Reference, p. 985, copyright 1978.
Pentikainen et al., American Review of Respiratory Disease, vol. 108, 1973.
Wagner et al., American Review of Respiratory Disease, vol. 108, 1973.
Colbert, J. C., Controlled Action Drug Forms, 1974.
Lehman, K., Pharma. International, 3, 1971, pp. 1-16.
Schroeter, L., Remington's Pharmaceutical Sciences, 14th Ed., Chapter 88, 1970.
Ellis et al., The Theory and Practice of Industrial Pharmacy, Chapter 10, 1970.
Alyushin, T., "Synthetic Polymers in Home Pharmaceutical Practice", Med., Moscow, 1974, p. 26.
Aghgikhin, I., "Medicine Technology", Med., Moscow, 1975, pp. 345, 346.
Globentyl 500 mg brochure, Apr. 1980.
Physician's Desk Reference, 32nd Ed., 1978, pp. 310, 1699, 1700, 516-519, 682, 683, 802-805, 1438, 1439, 1077.
Rees et al., Brit. Med. J., Oct. 6, 1979, pp. 835-836.
Martindale, The Extra Pharmacopoeia, 1972, pp. 1766-1767.
Dew et al., Brit. Med. J., 287, Jul. 2, 1983, pp. 23-24.
Brown, J. Med. Chem., 26, 1983, pp. 1300-1307.
Dew et al., Brit. Clin. Pharmac., 16, 1983, pp. 185-187.
Nielsen et al., Scand. J. Gastroenterol., 18(86):56, (1983).
Rasmussen et al., Scand. J. Gastroenterol., 18(86):63, (1983).
Dew et al., Brit. J. Clin. Pharmac., 17:474-76, (1984).
Campieri et al., Abstracts of Papers: 1039, May 1984.
Selby et al., Digestion, 29:231-34, (1984).
Campieri et al., Digestion, 29:204-08, (1984).
Donald et al., Postgrad. Med. J., 61:1047-48, (1985).
Klotz et al., Drug Res., 35(1):636-37, (1985).
Habal et al., Abstracts of Papers: 1409, May 1985.
Bondesen et al., Scand. J. Gastroenterol., 21(6):693-700, (1986).
Wolman et al., Am. J. Gastroenterol., 81(9):877, (1986).
Saverymuttu et al., Digestion, 33:89-91, (1986).
Wellman et al., GUT, 27:814-20, (1986).
Powell-Tuck et al., Brit. Med. J. 272:599-602, Mar. 1, 1986.
McLeod et al., Gastroenterology, 90(5)(2):1546, May 1986.
Schroeder et al., Gastroenterology, 90(5)(2): 1620, May 1986.
Tremaine et al., Gastroenterology, 90(5)(2):1670, May 1986.
Guarino et al., Abstracts of Papers: 1441, May 1986.
Friedman et al., Am. J. Gastroenterology, 81(6):412-18, Jun. 1986.
Bondesen et al., Scand. J. Gastroenterol. Suppl., 21(120):6, (1986).
Skarberg et al., Lakartidningen, 63(34):3122-23, (1986).
Bull et al., Gastroenterology, 76(3): 607-21, (1979).
Van

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