Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Patent
1994-07-21
1996-08-06
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
4241301, A61K 39395
Patent
active
055431453
ABSTRACT:
A pharmaceutical composition suitable for administration to human beings for suppressing the production of factor VIII inhibitor includes:
REFERENCES:
patent: 4140679 (1979-02-01), Malley
patent: 4234569 (1980-11-01), Marsh
patent: 4344938 (1982-08-01), Sedlacek et al.
patent: 4545986 (1985-10-01), Malley
patent: 4564600 (1986-01-01), Ali et al.
patent: 4649132 (1987-03-01), Zimmerman
patent: 4670543 (1987-06-01), Bourgois et al.
patent: 4714759 (1987-12-01), Whitaker
Lazarchick et al., J. Clin. Invest., 60 (1977), pp. 1070-1079.
Kasper, Factor VIII Inhibitors, edited by Hoyer, published by A. R. Liss, Inc., New York, N.Y. (1984), pp. 87-98.
Foster et al., J. Clin. Investigation, 82, (1988), pp. 123-128.
Fulcher et al., Blood, 69, No. 5 (1987), pp. 1475-1480.
Shima et al., Brit. J. Hematol., 70, (1988), pp. 63-69.
Rotblat et al., Biochemistry, 24 (1985), pp. 4294-4300.
Allain et al., Thrombos. Hemostas., 45, No. 3 (1981), pp. 285-289.
Lazarchick et al., Annals of Clinical and Laboratory Science, 16, No. 6 (1986), pp. 497-501.
Lazarchick and Hoyer, J. Clin. Invest., 62, (1978), pp. 1048-1052.
Nilsson et al., The New England J. of Medicine, 318 (1988) pp. 947.
Nilsson et al., Thromb. & Hematol., 58 No. 1 (1987), p. 519.
Goodall et al., Thrombosis & Hematol., 54 No. 4 (1985), pp. 878-891.
de la Fuente et al., Blood, 64, No. 3 (1984), pp. 672-678.
Moffatt et al., Brit. J. of Hematol., 71 (1989), pp. 85-90.
Tiarks et al., Thrombosis Research, 45 (1987) pp. 527-537.
Sultan et al., The Lancet, (Oct. 6, 1984), pp. 765-768.
Barkas et al., J. Clin. Lab. Immunol., 7 (1982), pp. 223-227.
Borel et al., Annals New York Academy of Sciences, (1986) pp. 296-305.
Caulfield et al., J. Immunol., 138, No. 11 (1987), pp. 3680-3683.
Allain, Scand. J. Hematol., 33, suppl. 40 (1984), pp. 177-179.
"Suppression of Reaginic Antibody Formation, IV, Suppression of Reaginic Antibodies to Penicillin in the Mouse", Weng Y. Lee et al., The Journal of Immunology, vol. 117, No. 3, Sep. 1976, pp. 927-934.
"Tolerization of B.sub..epsilon. Cells by Conjugates of Haptens and Isologous .gamma.-Globulins", Weng Y. Lee et al., Cellular Immunology 58, 385-397 (1981).
"`ALERGIM`, A Specific Immune Complex for the Intraseasonal Treatment of Pollinosis. A Clinical Trial", E. G. Seropian et al., Abstracts Interlaken 1984--6th European Immunology Meeting, p. 325 (1984).
"Alergim.sup.R --A New Antiallergic Product Which Down-Regulates B Lymphocyte Functions", G. Szegli et al., Arch. Roum. Path. Exp. Microbiol., T. 46, No. 1, pp. 73-82, Jan.-Mar. 1987.
"Regulatory Effect of Antibody on the Immune Response", Jonathan W. Uhr et al., Advances in Immunology vol. 8, pp. 81-127, 1968.
Bernstein, I. L., et al., "Immunoregulatory Function of Specific IgG", Int. Archs. Allergy Appl. Immun., 58: 30-37 (1979).
E. Seropian et al., "`Alergim`--Blocking Antibody IgG Specific in Intraseasonal Treatments of Pollenosis: Clinical Results", Imunologie XIII, Academia De Stiinte Medicale Comisia Nationala De Imunologie Subcomisia Tirgu Mures 1984.
Andrew F. Geczy, et al, "Suppression of Reaginic Antibody Formation in Guinea Pigs by Anti-idiotypic Antibodies," J. Allergy Clin Immunol, vol. 62(5): 261-270, 1978.
G. G. B. Klaus, "Antigen-antibody Complexes Elicit Anti-Idiotypic Antibodies to Self-Idiotopes," Nature, vol. 272, pp. 265-266, Mar. 16, 1978.
Kurt Blaser, et al, "Suppression of Phoshorylcholine-Specific IgE Antibody Formation in BALB/c Mice by Isologous Anti-T 15 Antiserum," Eur. J. Immunol. 1979.9:1017-1020.
Kurt Blaser, et al, "Suppression of the Benzylpenicilloyl-(BPO) Specific IgE Formation With Isologous Anti-Idiotypic Anti-bodies in BALB/c Mice," The Journal of Immunology, vol. 125, No. 1, pp. 24-30, Jul., 1980.
K. Blaser, et al, "Investigation of a Syngeneic Murine Model for the Study of IgE Antibody Regulation With Isologous, Antiidiotypic Antibodies," Int. Archs Allergy Appl. Immun. 64: 42-50 (1981).
Raif S. Geha, M.D., "Current Concepts in Immunology," The New England Journal of Medicine, vol. 305, No. 1, pp. 25-28, Jul. 2, 1981.
A. I. Farkas, et al, "Immunogenicity of Antigen Complex With Antibody," Immunology, vol. 45, pp. 483-492, 1982.
Raif S. Geha & Marc Comunale, "Regulation of Immunoglobulin E Antibody Synthesis in Man by Antiidiotyic Antibodies," J. Clin. Invest., vol. 71, pp. 46-54, Jan., 1983.
Paul D. Buisseret, "Allergy," Scientific American, pp. 82-91, Aug., 1982.
Howard J. Sanders, "Allergy, A Protective Mechanism Out of Control," Chemical & Engineering News, vol. 48, pp. 84-135, May 11, 1970.
"Primer on Allergic and Immunologic Diseases," Journal of the American Medical Association, vol. 248, No. 20, Nov. 26, 1982.
E. P. Hall et al., "Regulation of rat IgE responses by immune complexes", Immunology, vol. 61 (1987), pp. 415-419.
Arend et al, "In Vitro Adherence of Soluble Immune Complexes to Macrophages", 136 J. Exp. Med. 514 (1972).
Klaus, "Cooperation Between Antigen-Reactive T Cells and Anti-Idiotypic B Cells in the Anti-Idiotypic Response . . . " 278 Nature 354 (Mar. 22, 1979).
Klaus, "Generation of Memory Cells, III. Antibody Class Requirements for the Generation of B-Memory Cells by Antigen-Antibody . . . " 37 Immunology 345 (1979).
Caulfield et al, "Induction of Idiotype-Specific Suppressor T Cell with Antigen/Antibody Complexes", 157 J. Exp. Med. 1713 (1983).
Blaser et al, "Immune Networks in Immediate Type Allergic Diseases", 418 Ann. NY Acad.Sci. 330 (1983).
Blaser et al, "Regulation of the IgE Antibody Response by Idiotype-Anti-Idiotype Network", 32 Prog. Allergy 203 (1982).
Blaser et al, "Regulatory Effects of Isologous Anti-idiotypic Antibodies on the Formation of . . . ", 14 Eur. J. Immunol. 93-98 (1984) 50 Fed. Reg. 3082 (Jan. 23, 1985).
Fox, Nature 314, 1985, pp. 132-133.
Gene Cloning, 1984, ed. Glover, pp. 102-104.
Principles of Gene Manipulation, 1981, ed. Old et al., pp. 104-105, 119-120.
Brackmann, H. H. et al., "Massive Factor-VIII Infusion In Haemophiliac With Factor-VIII Inhibitor, High Responder", The Lancet, vol. 2, p. 933 (1977).
Kingdon Henry S.
Lebeque Serge
Lebrun Philippe
Masson Pierre L.
Saint-Remy Jean-Marie
Baxter International Inc.
Henley III Raymond
International Institute of Cellular and Molecular Pathology
LandOfFree
Pharmaceutical composition and method for the suppression of fac does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical composition and method for the suppression of fac, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition and method for the suppression of fac will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2189395