Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-09-19
1992-07-28
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3140
Patent
active
051341565
ABSTRACT:
Actinonin or a salt thereof is active as an inhibitor of angiogenesis in a mammal and is useful as a therapeutic agent for inhibiting angiogenesis in a mammal having diabetic retinopathy or inflammatory response accompanied by angiogenesis.
REFERENCES:
patent: 4663342 (1987-05-01), Umezawa et al.
Journal of Cancer Research and Clinical Oncology, vol. 116, suppl., 16th-22nd Aug. 1990, p. 14, abstract No. Al.064.05, Hamburg, Germany; M. Shimamura, et al: "Actinonin a proteinase inhibitor, potently inhibits angiogenesis", p. 14.
Aoyagi Takaaki
Iwaguchi Takao
Shimamura Mariko
Takeuchi Tomio
Uchida Shingo
Goldberg Jerome D.
Zaidan Hojin Biseibutsu Kagaku Kai
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