Pharmaceutical composition and method for angiogenesis inhibitio

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3140

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active

051341565

ABSTRACT:
Actinonin or a salt thereof is active as an inhibitor of angiogenesis in a mammal and is useful as a therapeutic agent for inhibiting angiogenesis in a mammal having diabetic retinopathy or inflammatory response accompanied by angiogenesis.

REFERENCES:
patent: 4663342 (1987-05-01), Umezawa et al.
Journal of Cancer Research and Clinical Oncology, vol. 116, suppl., 16th-22nd Aug. 1990, p. 14, abstract No. Al.064.05, Hamburg, Germany; M. Shimamura, et al: "Actinonin a proteinase inhibitor, potently inhibits angiogenesis", p. 14.

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