Pharmaceutical composition against AIDS

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds specifically-identified oligosaccharide structure

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5303875, 43524027, A61K 39395, C07K 1618, C12N 512

Patent

active

055715125

ABSTRACT:
A pharmaceutical composition against AIDS, which contains, as an active ingredient, an antibody capable of recognizing glycolipid derived from Echinoidea.

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"Isolation And Characterization of A Novel Phytosphingosine-Containing . . . ,", Journal of Biological Chemistry, 258;14;8980-85, Jul. 1984.
Hansen et al., "Inhibition of Human Immunodeficiency Virus (HIV) Infection In Vitro by Anticarbohydrate Monoclonal Antibodies: Peripheral Glycosylation of HIV Envelope Glycoprotein gp120 may be a Targer for Virus Neutralization", Journ. of Virology, vol. 64, No. 6, Jun. 1990, pp. 2833-2840.
Adachi et al., "Expression of Le.sup.y Antigen In Human Immunodeficiency Virus-Infected Human T Cell Lines and in Peripheral Lymphocytes of Patients With Acquired Immune Deficiency Syndrome (AIDS) and Aids-Related Complex (ARC)", Journ. Exp. Med., vol. 167, No. 2, Feb. 1988 pp. 323-331, (1988).
Adachi, "Expresion of Le.sub.y Antigen in Human Immunodeficiency Virus-Infected Human T Cell Lines and in Peripheral Lymphocytes of Patients with Acquired Immune Deficiency Syndrome (Aids) and Aids-Related Complex (Arc)", Journ. Exp. Med., vol. 167, No. 2, Feb. 1988, pp. 323-331.

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