Pharmaceutical composition

Details Pharmaceutical composition Pharmaceutical composition

1991-02-26

1992-10-20

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424456, 424461, 424480, A61K 962

Patent

active

051568497

ABSTRACT:
A pharmaceutical product preferably in the form of a capsule comprises in one case Atenolol and aspirin. A barrier film coating including a dihydric alcohol is provided around a tablet of Atenolol which in turn is surrounded by Aspirin inside a capsule. Aspirin is preferentially and maximally absorbed in the first hour after ingestion before significant release and absorbtion of Atenolol.

REFERENCES:
patent: 2965541 (1959-12-01), Byrnes
patent: 4315924 (1982-02-01), Perrot
patent: 4464377 (1984-08-01), Blanchard et al.
patent: 4693896 (1987-09-01), Wheatley
patent: 4695466 (1987-09-01), Morishita et al.
patent: 4798811 (1989-01-01), Lehmann et al.
patent: 5032406 (1991-07-01), Dansereau et al.
Chemical Abstracts, vol. 98, May 1983, p. 375 185576g.
European Search Report.
United Kingdom Search Report.
Drug Facts & Comparisons ed. Covington, et al. Lipincott 1990 pp. 999,1003,1015.
Principles of Medicinal Chemistry, Foye, 1976, p. 540.
PDR, 1985 pp. 650,651,1802.

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