Pharmaceutical composition

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424449, 424447, A61F 1302

Patent

active

051185083

ABSTRACT:
The present invention relates to a pharmaceutical composition in a form of a film. The composition comprises (a) a butyrophenone compound and (b) a vehicle comprising polyvinyl acetal diethylaminoacetate and polyvinyl pyrrolidone. The ratio of the compound to the vehicle is from 1% to 80% by weight based on the total weight of the vehicle and the ratio by weight of polyvinyl acetal diethylaminoacetate and polyvinyl pyrrolidone is from 1:9 to 9:1. The pharmaceutical composition can be applied to the skin of a patient for a long time and maintain a therapeutically effective blood level of the butyrophenone.

REFERENCES:
patent: 4565821 (1986-01-01), Chion
patent: 4593048 (1986-06-01), Sato et al.
patent: 4710497 (1987-12-01), Heller et al.
patent: 4752612 (1988-06-01), Saito et al.
patent: 4863952 (1989-09-01), Abe et al.
Organic-Chemical Drugs and Their Synonyms, 6th edition, 1987, M. Negwer.

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