Pharmaceutical composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514355, 514563, 514357, A61K 3144

Patent

active

055367356

ABSTRACT:
This invention comprises a pharmaceutical composition comprising a benzimidazole compound having antiulcer activity and a water-soluble carboxylic acid amide. According to this invention, a water-insoluble benzimidazole compound having antiulcer activity can be solubilized and a stable pharmaceutical composition can be provided. The solid pharmaceutical composition of this invention can be extemporaneously dissolved in sterile distilled water or an infusion (e.g. physiological saline, glucose infusion, etc.) and put to use as an injection with great convenience.

REFERENCES:
patent: 4628098 (1986-12-01), Nohara et al.
patent: 4954512 (1990-09-01), Oguro et al.
patent: 5223515 (1993-06-01), Mikura et al.
Howden et al 109CA:85750m 1988.
Am. J. Hosp. Pharm., 46, (1989).

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