Pharmaceutical composition

Drug – bio-affecting and body treating compositions – Manicure or pedicure compositions

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Details

514858, A61K 7043, A61K 704

Patent

active

058661050

ABSTRACT:
The invention concerns topical formulations such as nail varnishes comprising as the active agent the compound of formula I ##STR1## in free base form or in acid addition salt form, together with a polymeric film former and further excipients as appropriate. It also concerns a process of preparation of such preparations by mixing with an appropriate polymeric film former and conventional further excipients as appropriate, and a method of treatment of onychomycosis.

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patent: 5057312 (1991-10-01), Langlia
patent: 5106878 (1992-04-01), Guerry et al.
patent: 5116603 (1992-05-01), Friedman
patent: 5120530 (1992-06-01), Ferro
patent: 5132459 (1992-07-01), Stuetz
patent: 5160737 (1992-11-01), Friedman
G. Petranyi et al., Antimicrobial Agents and Chemotherapy, vol. 31, No. 10, 1987, pp. 1558-1561.
Merck Index, 11th edition, 1989, p. 1442.
R. Savin, Clinical and Experimental Dermatology, vol. 14, 1989, pp. 116-119.
V. Villars and TC Jones, Journal of Dermatological Treatment, vol. 1, Suppl. 2, 1990, pp. 33-38.
TC Jones, Journal of Dermatological Treatment, vol. 1, Suppl. 2, 1990, pp. 29-32.

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