Pharmaceutical composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

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Reexamination Certificate

active

07608607

ABSTRACT:
A pharmaceutical composition comprising: (A) an androgen; (B) a cyclic enhancer of the type used in the compositions and methods claimed by U.S. Pat. No. 5,023,252 to Hsieh; and (C) a thickening agent; including, for example, a composition in which the cyclic enhancer is a macrocyclic ester or a macrocyclic ketone; the use of the composition to treat a condition, for example, male hypogonadism, in a patient by applying the composition to the membrane of the patient; and a method for making the composition.

REFERENCES:
patent: 5019395 (1991-05-01), Mahjour et al.
patent: 5023252 (1991-06-01), Hseih
patent: 5855905 (1999-01-01), Oettel et al.
patent: 5968919 (1999-10-01), Samour et al.
patent: 6238284 (2001-05-01), Dittgen et al.
patent: 6503894 (2003-01-01), Dudley et al.
patent: 6743448 (2004-06-01), Krgyer
patent: 2002/0058650 (2002-05-01), Mak et al.
patent: 2003/0027804 (2003-02-01), van der Hoop
patent: 2008/0103120 (2008-05-01), Gyurik
patent: 2008/0108590 (2008-05-01), Gyurik
patent: 2008/0275012 (2008-11-01), Gyurik
Wang, C., et al., Pharmacokinetics of Transdermal Testosterone Gel in Hypgonadal Men: Application of Gel at One Site Versus Four Sites: A General Clinical Research Center Study, The Journal of Clinical Endocrinology & Metabolism, 2000, pp. 964-969, vol. 85, No. 3.
Wang C., et al., Transdermal Testosterone Gel Improves Sexual Function, Mood, Muscle Strength, and Body Composition Parameters in Hypogonadal Men, The Journal of Clinical Endocrinology & Metabolism, 2000, pp. 2839-2853, vol. 85, No. 8.
Cutter, C., Compound Percutaneous Testosterone Gel: Use and Effects in Hypogonadal Men, The Journal of American Board Family Practice, Jan.-Feb. 2001, pp, 22-32, vol. 14, No. 1.
Docket for litigation of parent application U.S. Patent No. 7,320,968 (docket retrieved on May 20, 2009).
Complaint for Patent Infringement filed on Dec. 4, 2008 for litigation of parent application U.S. Patent No. 7,320,968.

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