Pharmaceutical component based on human parathyroid hormone...

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Endocrine system – other than the thymus gland

Reexamination Certificate

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Details

C514S012200, C514S021800, C530S324000

Reexamination Certificate

active

07087248

ABSTRACT:
A medical component comprising a human parathyroid hormone peptide or its derivative, and acetic acid contained at a concentration less than its chemical equivalent with respect to the human parathyroid hormone peptide or to its derivative. Since in the medical component acetic acid, which is present as a salt of or attached to the peptide or its derivative, has been reduced to an amount less than chemical equivalent with respect to the human parathyroid hormone peptide or its derivative, a medical component, which is highly stable and will ensure an excellent use feeling when introduced into a pharmaceutical composition, is obtained.

REFERENCES:
patent: 4086196 (1978-04-01), Tregear
patent: 5856138 (1999-01-01), Fukuda
patent: 5977070 (1999-11-01), Piazza et al.
patent: 515228 (1992-11-01), None
patent: 672682 (1995-09-01), None
patent: 64-16799 (1989-01-01), None
patent: 97/14429 (1997-04-01), None
W. M. Law, Jr., et al. “Preparation of Synthetic Bovine Parathyroid Hormone Fragment 1-34 for Pareneral use in Human Studies;”Journal of Clinical Endocrinology and Metabolism, vol. 56, No. 6, pp. 1335-1337 (1983).
Muawia M. Ibrahim, et al. “Maintenance of Normocalcemia by Continuous Infusion of the Synthetic Bovine Parathyroid Hormone (1-34) in Parathyroidectomized Rats;”Calcified Tissue International, vol. 34, No. 6, pp. 553-557 (1982).

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