Pharmaceutical combinations comprising a fungicide, a...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Biocides; animal or insect repellents or attractants

Reexamination Certificate

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Reexamination Certificate

active

07811599

ABSTRACT:
Medical combination and its method of topical use comprising active ingredients which are sparingly soluble in water, preferably in one single composition against microbes which are pathogenic in humans and animals and which usually appear together. It comprises at least one active ingredient which is effective against several of the opportunally pathogenic strains of the group consisting of fungiCandida, Aspergillus, and/orFusarium, and aerobic bacteria: Gram-negative bacilli such asProteus, Pseudomonas, enterobacterspecies,Escherichia coli, Klebsiella, Serratia marcescens, Citrobacter, Aeromonas; Gram-negative cocci such asNeisseria, Acinetobacterspecies; Gram-positive bacilli such asCorynebacteriumspecies,Bacillus sphaericus, Gram-positive cocci such asStreptococcusspecies; anaerobic bacteria: Gram-negative cocci such asBacteroides, Fusobacteria; Gram-positive cocci such asPeptococcus, Peptostreptococcusspecies; Gram-positive bacilli such asClostridium, Propionibacterium, Eubacteriumspecies andMycobacteriumspecies such asMycobacterium ulcerans, microbes similar to bacteria of theChlamydiaspecies such asChlamydia trachomatis. To be used for treatment of the skin or mucous membranes bearing epithelial lesions, deficiency or injuries and to be used in body cavities to prevent or cure infections and deficiencies. The composition contains-dispersed in a carrier which is pharmaceutically acceptable on the site of treatment-at least one fungicide, which is preferably azole or polyene type and at least one antibacterial compound preferably of the erythromycin, azalide, linkozamide, polypeptide type and at least one bacteriostatic sulphonamide. Additionals mainly for use on skin may include zinc oxide and asulene. Useful in forms of ointment, tablet, effervescent tablet, suppository, foam.

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International Search Report for International Publication No. PCT/HU02/00115. Date of Mailing: Mar. 6, 2003.

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