Pharmaceutical carrier

Details Pharmaceutical carrier Pharmaceutical carrier

1995-05-31

1997-02-18

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424484, A61K 916

Patent

active

056039581

ABSTRACT:
The invention refers to the use of an inert, structure-giving, deadjuvanated matrix of a complex of a sterol, such as cholesterol, and one or more saponins as a carrier for the administration of a pharmaceutically active substance, and a drug carrying particle comprising said inert structure-giving matrix to which has been connected a pharmaceutically active substance. The drug carrying particle, delpha, has an annular basic structure which can form spherical nano particles having a size of 30-50 nm and a narrow size distribution.

REFERENCES:
patent: 4900549 (1990-02-01), De Vries
patent: 5077057 (1991-12-01), Szoka
patent: 5196192 (1993-03-01), Kretser
Biotechnology and Applied Biochemistry, vol. 10, 1988, pp. 161-172.
Biochimica et Biophysica Acta, vol. 1062 (1991), pp. 165-171.

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