Pharmaceutical capsules containing panetidine

Details Pharmaceutical capsules containing panetidine Pharmaceutical capsules containing panetidine

1990-02-22

1991-07-02

Page, Thurman

Material or article handling

Tilting vehicle-type handler

Opposed movable jaw grippers

414456, 414484, A61K 948

Patent

active

050284320

ABSTRACT:
The invention relates to a pharmaceutical composition in the form of a gelatin capsules consisting of a filling containing as active ingredient ranitidine or a physiologically acceptable salt thereof surrounded by a gelatin shell. The filling is formulated based on a non-aqueous matrix consisting of at least one fatty acid glyceride and/or mineral oil or paraffin. Preferably the matrix contains at least one surfactant. The matrix is essentially hydrophobic in character but is also sufficiently hydrophilic to permit dispersion and dissolution of the capsule filling in the gastrointenstinal tract.

REFERENCES:
patent: 4128658 (1978-12-01), Price et al.
patent: 4521431 (1985-06-01), Crookes
patent: 4610990 (1986-09-01), Esanu
Lachman et al., "The Nature of the Capsule Content", The Theory and Practice of Industrial Pharmacy, (2nd Edition), (1976), pp. 408-413.
The Pharmaceutical Codes (11th Edition) The Pharmaceutical Press, London, (1979) pp. 133-134.

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