Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Milk or colostrum
Patent
1995-08-14
1998-05-12
Witz, Jean C.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Milk or colostrum
424DIG13, 530832, A61K 3520
Patent
active
057501491
DESCRIPTION:
BRIEF SUMMARY
The present invention refers to pharmaceutical, dermatological and cosmetic compositions containing equine colostrum optionally in admixture with equine milk or derivatives of equine colostrum or milk.
In the following description, the term "equine" preferably refers to horses although other equine species can be used as sources of colostrum (or milk) according to the invention.
Colostrum is defined according to the invention as the mammary secretion occurring in the period starting from some days before delivery until some days after delivery, characterized by an immunoglobulin content of at least 1000 mg/dl. In certain phases of the secretion, this content may be remarkably higher.
The pharmaceutical and/or dermocosmetological and cosmetic compositions of the invention contain therefore either equine colostrum as above defined or mixtures of colostrum and milk, in weight ratios ranging from 1:10 to 3:1, preferably from 1:9 to 2:1.
It has been found that the compositions of the invention, when topically applied on the skin, are particularly effective in the treatment of burns (caused by fire or sunlight), contact lesions (caused by jelly fishes or, generally by vescicant agents), of cutaneous diseases such as acne, seborrhoic dermatitis, irritations, dyscheratosis and dysmetabolic, dyspepsic forms, such as vascular cutaneous dystrophy, keratinization defects (psoriasis, ichtyosis), chronic photodamages, atopic dermatitis, senile itching, photoerythema and other common dermatological diseases.
According to the invention, equine colostrum and milk may also be formulated, in the above specified ratios, into cosmetic compositions having anti-burn, anti-lines, antiaging, moisturizing, protective, tensio-distensive, tonic, anti-relaxant, smoothing, anti-irritant, emollient, decongestionant, sun filtering, bleaching, lenitive sebum normalizing activities, repairing activity of damages by sun or radiant rays or generally by physical a chemical damages.
Thanks to their lenitive and anti-irritant action, the compositions of the invention may be effectively used, for instance, in cases of irritation of infants or children's skin caused by diapers, irritation after shave, and in all cases of irritation caused by atmospheric agents (sun, wind, cold etc).
Thanks to their tonic, distensive action on wrinkles, the compositions of the invention may be effectively used for the treatment of aging processes of the skin (antiaging action) caused both by physiological and by exogenous causes, such as noxious UV radiations, atmospheric agents, pollution etc. Thanks to their nutritive and sebumnormalizing action, the compositions of the invention may also be used in the treatment of diseases of the scalp and of hair, particularly of seborrhoic dermatitis and consequent alopecia; dandruff; fragility, dryness of the hair and split hairs due to decoloration or perm processes or the like.
The compositions of the invention are also useful for the prevention and treatment of cellulitis, couperouse and hair loss and, because of their healing and antiallergic action, for the treatment of burns, erythemas etc.
Examples of compositions of the invention comprise creams, lotions, tonic lotions, emulsions, ointments, gels, masks, foams, milks, detergent milks, aspersory pourders, sun- and after-sun creams, oils, shampoos, hair conditioners, packs lipsticks, after-shave creams and lotions, and the like.
The compositions of the invention typically contain from 1 to 50% by weight of equine colostrum (or mixtures thereof with equine milk in the above specified ratios) according to the intended uses, with suitable excipients and adjuvants.
Formulations consisting of pure equine colostrum (distributed, for instance, in vials or bottles) may also be provided.
Extractive or semi-synthetic derivatives of colostrum may also be used.
Moreover, the compositions of the invention may also optionally contain other active agents, having complementary or anyhow useful activity, such as anti-inflammatory, antibacterial, moisturizing, emollients, healing, repa
REFERENCES:
patent: 4342747 (1982-08-01), Lioteb et al.
patent: 4970072 (1990-11-01), Honda et al.
Horse Vitality Ltd
Schneider Walter H.
Witz Jean C.
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