Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-09-03
1996-01-09
Haley, Jacqueline
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548507, A61K 3140, C07D20912
Patent
active
054829631
ABSTRACT:
The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.
REFERENCES:
T. S. Kondrat'eva, The Technology of Therapeutic Forms, "Meditsina" 1991, pp. 85-88, (and translation thereof).
I. M. Rabinovich, The Use of Polymers in Medicine, "Leningrad Meditsina", 1972, pp. 16-17, (and translation thereof).
Bradway Randy J.
Clements Arlene
Edwards Ieuan J.
Holohan James J.
Timko Robert J.
Haley Jacqueline
Zeneca Limited
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