Phagemid vectors

Details Phagemid vectors Phagemid vectors

2011-02-08

2011-02-08

Dunston, Jennifer (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C536S023100, C536S023400, C536S023700, C536S024100, C536S023200, C435S069100, C435S005000

Reissue Patent

active

RE042130

ABSTRACT:
Phagemid vectors containing a sequence of features between a Col E1 origin and an f1 origin are useful for display of polypeptides or proteins, including antibody libraries.

REFERENCES:
patent: 5658727 (1997-08-01), Barbas et al.
patent: 6113896 (2000-09-01), Lazarus et al.
patent: 6346394 (2002-02-01), Mitsuzumi et al.
patent: WO-95/11317 (1995-04-01), None
patent: WO-2000/71694 (2000-11-01), None
patent: WO-2004/078937 (2004-09-01), None
Mattanovich et al. Optimization of recombinant gene expression in Escherichia coli. Annals of the New York Academy of Sciences, vol. 782, pp. 182-190, 1996.
Alting-Mees, Ma et al., Methods in Enzymology “PBluescriptll: multifunctional cloning and mapping vectors”, vol. 216, pp. 483-495 (1992).
Barbas III et al., “Pharge Display: A Laboratory Manual”, Cold Spring Harbor Press, (2001).
Genbank Entry Number AF268280.1 (sequence of pComb3H vector) available on National Center fro Biological Information database (2000).
Genbank Entry Number AF268280.1 (sequence of pComb3X vector) available on National Center fro Biological Information database (2000).
Krebber, A. et al., Inclusion of an upstream transcriptional terminator in phage display vector abolishes background expression of toxic fusions with coat protein g3p Gene, 178 (1996) 71-74.
Lewin, Gene, Chapter 13, pp. 202-216 (1983).
Mamoru, W. et al., Protein Expression and Purification, “Overproduction of D-Aminoaclase from Alcalugenes xylosoxydans subsp. xylosoxydans A-6 in Escherichia coli and Its Purification”, 7: 395-389 (1996).
Map of pComb3H vector. printed in 2006.
Map of pComb3X vector.printed in 2006.
Print-out from Amazon.com website showing publication of Chapter 2 of “Phage Display: A Laboratory Manual”, dated Jan. 15, 2001.
Rader, C. et al., Current Opinion in Biotechnology “Phage Display of Combinatorial Antibody Libraries”, 8: 503-508 (1997).
Table of features of pComb3X and pComb3H vectors relative of claim 1 of EP-B-1390489, 2006.
Weiss, Ga et al., JMB, “Design and Evolution of Artificial M13 Coat Proteins”, 300: 213-219 (2000).
Zimmerman et al., Protein Expression and Purification, “High-Level Expression of Rat Farnesyl: Protein Transferase in Escherichia Coli as a Translationally Coupled Heterodimer”, 14: 395-402 (1998).
Gao et al., “Making artificial antibodies: A format for phage display of combinatorial heterodimeric arrays”, Proc. National Acad. Sci. USA, vol. 96, pp. 6025-6030 (1999).
Gao et al., “Making chemistry selectable by linking it to infectivity”, Proc. National Acad. Sci. USA, vol. 94, pp. 11777-11782 (1997).
Minute of the Oral Proceedings in EP Patent No. B-1390489 (App. No. 02 734 056.1) dated Dec. 17, 2008.
Krebber et al., Gene, 1996, vol. 178, pp. 71-74.
“Genes”, Benjamin Lewis, Ed., John Wiley & Sons, Inc., Chapter 13, “Termination and Antitermination”, pp. 202-216.

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