Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1999-10-07
2000-10-03
McKelvey, Terry
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4353201, G01N 3353, C12N 1570
Patent
active
061271322
ABSTRACT:
A phagemid has been constructed that expresses an antibody fused to coliphage pIII protein. The phagemid is suitable for selecting specific antibodies from large gene libraries with small quantities of antigen. The antibody-pIII gene can be strongly repressed, so that it allows antibody libraries to be amplified without the danger of deletion mutants predominating. After induction, large quantities of the fusion protein may be expressed.
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Braunagel Michael
Breitling Frank
Dubel Stefan
Klewinghaus Iris
Little Melvyn
Deutsches Krebsforschungszentrum Stiftung des offentlichen Recht
McKelvey Terry
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