Phage resistant bacteria

Details Phage resistant bacteria Phage resistant bacteria

2000-08-08

2008-10-14

Prouty, Rebecca E. (Department: 1652)

Food or edible material: processes, compositions, and products

Dormant ferment containing product, or live microorganism...

C435S253400, C435S235100, C435S252300, C424S093600, C424S093440

Reexamination Certificate

active

07435434

ABSTRACT:
The invention relates to anS thermophilusbacterium which is resistant to attack by at least one bacteriophage, a method of production of the bacterium and a composition which comprises the bacterium. The bacterium comprises a modification of the Sfi21 prophage or the bacterial genome which disrupts expression of a gene which is essential to a bacteriophage, but not essential to the bacteria.

REFERENCES:
patent: 0 183 469 (1986-04-01), None
patent: 0 748 871 (1996-12-01), None
Document No. XP-002163736 Entitled: “A Short Noncoding Viral DNA Elements Showing Characteristics of a Replication Origin Confers Bacteriophage Resistance toStreptococcus thermophilus,” Virology250, 377-387 (1998).
Document No. XP002163737 Entitled: “Broad-Range Bacteriophage Resistance inStreptococcus thermophilusby Insertional Mutagenesis,”Virology275, 267-277 (2000).
Document No. XP-000673892 Entitled: “Efficient Insertional Mutagenesis inLactococciand Other Gram-Positive Bacteria,”Journal of Bacteriology, Feb. 1996, p. 931-935.

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