Phage-associated lytic enzymes for treatment of Bacillus...

Details Phage-associated lytic enzymes for treatment of Bacillus... Phage-associated lytic enzymes for treatment of Bacillus...

2008-07-22

2008-07-22

Ramirez, Delia M (Department: 1652)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C424S094670, C435S212000, C435S018000, C435S069100, C435S320100, C435S325000, C435S252300, C536S023200, C530S350000

Reexamination Certificate

active

07402309

ABSTRACT:
The present disclosure relates to methods, compositions and articles of manufacture useful for the treatment ofBacillus anthracisandB. cereusbacteria and spores, and related conditions. The disclosure further relates to methods and compositions for the identification of a phage associated lytic enzyme to rapidly and specifically detect and killBacillus anthracisand other bacteria. Related articles of manufacture, methods of degrading spores and methods of treatment of infections or bacteria populations of, or subjects exposed to or at risk for exposure to,Bacillus anthracisare also provided.

REFERENCES:
patent: 2002/0127215 (2002-09-01), Loomis et al.
patent: WO 03/010316 (2003-02-01), None
Branden et al., Introduction to Protein Structure, Garland Publishing Inc., New York, p. 247, 1991.
Witkowski et al., Biochemistry 38:11643-11650, 1999.
Seffernick et al., J. Bacteriol. 183(8):2405-2410, 2001.
Brown, Eric R. et al.; “Specific Identification ofBacillus Anthracisby Means of a Variant Bacteriophage”; United States Department of Health, Education and Welfare, Communicable Disease Center, Public Health Service, Chamblee, Georgia, pp. 34-39., 1954.
Nelson, Daniel et al.; “Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme”; Proc. Natl. Acad. Sci., 2001, vol. 98, No. 7, pp. 4107-4112.
Schuch, Raymond et al.; “A bacteriolytic agent that detects and killsBacillus anthracis;”Nature, vol. 418; Aug. 22, 2002; pp. 884-889.
Internet excerpt entitled “Bacteriophage;” New Horizons Diagnostics Inc.; obtained at the internet address: nhdiag.com/phage.shtml; Nov. 5, 2003; two pages.
Internet excerpt entitled “Bacteriophage;” New Horizons Diagnostics Inc.; obtained at the internet address: nhdiag.com/phage.shtml; Jan. 13, 2004; two pages.
Internet excerpt entitled “Bacillus anthracis(spore) Lateral Flow Screening Assay;” New Horizons Diagnostics Inc.; obtained at the internet address: nhdiag.com/anthrax.shtml; Jan. 13, 2004; two pages.

Affiliated with

Also associated with

Rating

Phage-associated lytic enzymes for treatment of Bacillus... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phage-associated lytic enzymes for treatment of Bacillus..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phage-associated lytic enzymes for treatment of Bacillus... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2798539