pH sensitive polymer for inhibiting transformation in drugs

Details pH sensitive polymer for inhibiting transformation in drugs pH sensitive polymer for inhibiting transformation in drugs

2007-10-16

2007-10-16

Kennedy, Sharon E. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

Reexamination Certificate

active

10739528

ABSTRACT:
The present invention discloses a substantially amorphous pharmaceutical composition comprising a drug that can exist in a variety of polymorphic forms and a pH sensitive polymer, which inhibits the crystallization of the drug during formulation and reconstitution. Polymers of higher molecular weight are more effective at lower loading, especially when the drug polymer matrix is prepared by the solvent evaporation or solvent extraction technique. The compositions used as dry syrups maintain bioavailability of the drug and effectively mask the taste of the drug when the composition is reconstituted.

REFERENCES:
patent: 3608063 (1971-09-01), Banker
patent: 4786508 (1988-11-01), Ghebre-Sellassie et al.
patent: 5116603 (1992-05-01), Friedman
patent: 5286489 (1994-02-01), Tsau et al.
patent: 5445830 (1995-08-01), Ishizue et al.
patent: 6372259 (2002-04-01), Kumar
patent: 6797768 (2004-09-01), Lyons
patent: 2003/0064108 (2003-04-01), Lukas et al.
patent: 2003/0220413 (2003-11-01), Petereit et al.
patent: 2005/0136114 (2005-06-01), Kulkarni et al.
patent: 2005/0137372 (2005-06-01), Kulkarni et al.
patent: 2005/0281874 (2005-12-01), Menjoge et al.
patent: 2006/0134054 (2006-06-01), Kulkarni et al.
patent: 2006/0141053 (2006-06-01), Menjoge et al.
patent: 0781551 (1997-07-01), None
patent: 1317925 (2003-06-01), None

Affiliated with

Also associated with

Rating

pH sensitive polymer for inhibiting transformation in drugs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with pH sensitive polymer for inhibiting transformation in drugs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and pH sensitive polymer for inhibiting transformation in drugs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3890478