Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1997-01-29
1998-09-22
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424465, 424474, A61K 928
Patent
active
058111212
ABSTRACT:
This invention is based on the discovery that certain cellulose acetoacetate mixed esters will remain insoluble in mild (near-neutral) or acidic aqueous solutions, but dissolve under alkaline conditions. The esters are particularly useful as coatings for controlled-release applications. Coatings comprising these esters will dissolve to release a coated active agent under alkaline conditions, the exact pH at which dissolution occurs being adjustable.
REFERENCES:
patent: 2500029 (1950-04-01), Hagemeyer
patent: 2521897 (1950-04-01), Caldwell
patent: 3908045 (1975-09-01), Alterman et al.
patent: 3944497 (1976-03-01), Alterman et al.
patent: 3983254 (1976-09-01), Alterman et al.
patent: 4078099 (1978-03-01), Mazzola
patent: 4124734 (1978-11-01), Alterman et al.
patent: 4126717 (1978-11-01), Mazzola
patent: 4136052 (1979-01-01), Mazzola
patent: 4762637 (1988-08-01), Aronson et al.
patent: 5000869 (1991-03-01), Dittert
patent: 5292783 (1994-03-01), Buchanan et al.
patent: 5446079 (1995-08-01), Buchanan et al.
patent: 5521304 (1996-05-01), Edgar et al.
patent: 5559171 (1996-09-01), Buchanan et al.
patent: 5580911 (1996-12-01), Buchanan et al.
Kuo Chung-Ming
Wu Stephen Hong-Wei
Eastman Chemical Company
Griffis Andrew B.
Gwinnell Harry J.
Page Thurman K.
Shelborne Kathryne E.
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