PGC-1β, a novel PGC-1 homologue and uses therefor

Details PGC-1β, a novel PGC-1 homologue and uses therefor PGC-1β, a novel PGC-1 homologue and uses therefor

2006-08-15

2006-08-15

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S252300, C435S320100, C536S023100, C530S300000, C530S350000

Reexamination Certificate

active

07091006

ABSTRACT:
The invention provides isolated nucleic acid molecules, designated PGC-1β nucleic acid molecules, which encode novel PGC-1 related coactivator molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1β nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1β gene has been introduced or disrupted. The invention still further provides isolated PGC-1β proteins, fusion proteins, antigenic peptides and anti-PGC-1β antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
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Accession No. AAD36095.
Accession No. AAE22761.

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