Peyer's patch and/or M-cell targeting ligands

Details Peyer's patch and/or M-cell targeting ligands Peyer's patch and/or M-cell targeting ligands

2005-07-12

2005-07-12

Russel, Jeffrey Edwin (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S184100, C424S192100, C424S196110, C424S197110, C424S450000, C514S002600, C514S012200, C514S013800, C530S300000, C530S324000, C530S327000, C530S350000

Reexamination Certificate

active

06916789

ABSTRACT:
Purified synthetic polypeptide ligands comprising a 12-mer L-peptide, D-peptides being the D-form of the 12-mer L-peptides, 12-mer retro-inverted peptides being the retro-inverted form of the 12-mer L-peptide, or fragments and homologues thereof, are disclosed. These ligands are for targeting pharmaceutical agents and carriers comprising such agents to intestinal epithelial tissue, especially Peyer's patch and/or M-Cell tissue. Methods of using the ligands are also disclosed.

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