Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1981-12-04
1982-11-02
Torrence, Dolph H.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
26045399, 424304, A01N 3728, A01N 3734, C07C11900, C07C12178
Patent
active
043573479
ABSTRACT:
Phenylcarbamoylbenzimidates of the formula ##STR1## wherein X.sub.1 is selected from the group consisting of methyl, trifluoromethyl, chlorine, fluorine and bromine; X.sub.2 is selected from the group consisting of hydrogen, methyl, trifluoromethyl, chlorine, fluorine and bromine; R is alkyl of from 1 to 5 carbon atoms; X.sub.3 and X.sub.4 can be the same or different and are selected from the group consisting of hydrogen, chlorine and bromine; X.sub.5 is selected from the group consisting of hydrogen, chlorine, bromine and trifluoromethyl; and X.sub.6 is selected from the group consisting of cyano and nitro; with the proviso that when X.sub.1 and X.sub.2 are chlorine or when X.sub.1 is fluorine and X.sub.2 is hydrogen then R, X.sub.3, X.sub.4, X.sub.5 and X.sub.6 are respectively not 1-methylethyl, chlorine, hydrogen, chlorine and nitro; with the further proviso that when X.sub.1 is fluorine and X.sub.2 is hydrogen then R, X.sub.3, X.sub.4, X.sub.5 and X.sub.6 are respectively not 1-methylethyl, chlorine, hydrogen, hydrogen and nitro; and with the further proviso that when X.sub. 1 is florine or methyl and X.sub.2 is hydrogen then R, X.sub.3, X.sub.4, X.sub.5 and X.sub.6 are respectively not ethyl, hydrogen, hydrogen, hydrogen and nitro; and with the proviso that when X.sub.1 and X.sub.2 are florine, then R, X.sub.3, X.sub.4, X.sub.5 and X.sub.6 are respectively not ethyl, chlorine, hydrogen, chlorine and nitro.
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R. Buyle et al., Helv. Chim. Acta., 46, 1073-1083 (1963).
Jameson William G.
The Upjohn Company
Torrence Dolph H.
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