PERV screening method and use thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S024300, C536S024320, C435S006120, C435S091200

Reexamination Certificate

active

07449562

ABSTRACT:
The invention relates to porcine endogenous retrovirus (PERV) and novel methods of identification, isolation and screening via polynucleotide sequences. It also relates to use of said methods in providing a pig that does not express porcine endogenous retrovirus. The organs, tissues and cells of said pig being capable of use for xenotransplantaion.

REFERENCES:
patent: 4980286 (1990-12-01), Morgan et al.
patent: 5166320 (1992-11-01), Wu et al.
patent: 5173414 (1992-12-01), Lebkowski et al.
patent: 5219740 (1993-06-01), Miller et al.
patent: 5252479 (1993-10-01), Srivastava
patent: 5413923 (1995-05-01), Kucherlapati et al.
patent: 5416260 (1995-05-01), Koller et al.
patent: 5552311 (1996-09-01), Sorscher et al.
patent: 5574205 (1996-11-01), Kucherlapati et al.
patent: 5604090 (1997-02-01), Alexander et al.
patent: 5658785 (1997-08-01), Johnson
patent: 5728399 (1998-03-01), Wu et al.
patent: 5763416 (1998-06-01), Bonadio et al.
patent: 5773289 (1998-06-01), Samulski et al.
patent: 5824544 (1998-10-01), Armentano et al.
patent: 5834182 (1998-11-01), Alexander et al.
patent: 5843742 (1998-12-01), Natsoulis et al.
patent: 5868040 (1999-02-01), Papenhagen et al.
patent: 5869040 (1999-02-01), Oin
patent: 5871722 (1999-02-01), Nacht et al.
patent: 5874297 (1999-02-01), Wu et al.
patent: 5880102 (1999-03-01), George et al.
patent: 5882877 (1999-03-01), Gregory et al.
patent: 5885808 (1999-03-01), Spooner et al.
patent: 5932210 (1999-08-01), Gregory et al.
patent: 5942496 (1999-08-01), Bonadio et al.
patent: 5948675 (1999-09-01), Klatzmann et al.
patent: 5981225 (1999-11-01), Kochanek et al.
patent: 5994106 (1999-11-01), Kovesdi et al.
patent: 5994132 (1999-11-01), Chamberlain et al.
patent: 6001557 (1999-12-01), Wilson et al.
patent: 6030954 (2000-02-01), Wu et al.
patent: 6033884 (2000-03-01), Woo et al.
patent: 6190861 (2001-02-01), Fishman
patent: 7038107 (2006-05-01), Cui et al.
patent: WO 92/06180 (1992-04-01), None
patent: WO 92/20316 (1992-11-01), None
patent: WO 92/22635 (1992-12-01), None
patent: WO 93/14188 (1993-07-01), None
patent: WO 93/20221 (1993-10-01), None
patent: WO 94/08598 (1994-04-01), None
patent: WO 9853104 (1998-11-01), None
patent: WO 00/71726 (2000-11-01), None
patent: WO 0071726 (2000-11-01), None
patent: WO 02/072836 (2002-09-01), None
Czauderna et al. J Virol 2000;74:4028-38.
Akiyoshi et al., “Identification of a Full-Length cDNA for an Endogenous Retrovirus of Miniature Swine”,J Virol, vol. 72, No. 5, pp. 4503-4507 (1998).
Animal Cell Culture: A Practical Approach, Second Edition, Freshney, Ed., IRL Press, Oxford University Press (1986).
Antibodies: A Laboratory Manual, Harlow and Lane, Eds., Cold Spring Harbor Press, NY (1988).
A Practical Guide to Molecular Cloning, Perbal, Ed., John Wiley & Sons, NY (1984).
Ausubel et al., “Preparing Lambda DNA from Phage Lysates”,Curr Prot Mol Biol, vol. 1, Unit 1.13, Suppl. 10, pp. 1.13.1-1.13.10 (1990).
Blusch et al., “Infection of Nonhuman Primate Cells by Pig Endogenous Retrovirus”,J Virol, vol. 74, No. 16, pp. 7687-7690 (2000).
Bösch, Arnauld and Jestin, “Study of Full-Length Porcine Endogenous Retrovirus Genomes with Envelope Gene Polymorphism in a Specific-Pathogen-Free Large White Swine Herd”,J Virol, vol. 74, No. 18, pp. 8575-8581 (2000).
Chee et al., “Accessing Genetic Information with High-Density DNA Arrays”,Science, vol. 274, No. 5287, pp. 610-614 (1996).
Colowick and Kaplan, “Methods in Enzymology, vol. 135: Immobilized Enzymes and Cells. Part B”, Mosbach, Ed., Academic Press, Inc. (1987).
Colowick and Kaplan, “Methods in Enzymology, vol. 155: Recombinant DNA, Part F”, Wu, Ed., Academic Press, Inc. (1987).
Cotton, Rodrigues and Campbell, “Reactivity of Cytosine and Thymine in Single-Base-Pair Mismatches with Hydroxylamine and Osmium Tetroxide and Its Application to the Study of Mutations”,Proc Natl Acad Sci USA, vol. 85, pp. 4397-4401 (1988).
Cozzi et al., Long-Term Survival of Nonhuman Primates Receiving Life-Supporting Transgenic Porcine Kidney Xenografts,Transplantation, vol. 70, No. 1, pp. 15-21 (2000).
Czauderna et al., “Establishment and Characterization of Molecular Clones of Porcine Endogenous Retroviruses Replicating on Human Cells”,J Virol, vol. 74, No. 9, pp. 4028-4038 (2000).
Deng et al., “Mapping Dispersed Repetitive Loci Using Semi-Specific PCR Cloning and Somatic Cell Hybrid Mapping”,Nucleic Acids Res, vol. 28, No. 23, e103, pp. 1-4 (2000).
Dexter, Allen and Lajtha, “Conditions Controlling the Proliferation of Haemopoietic Stem Cells in Vitro”,J Cell Physiol, vol. 91, No. 3, pp. 335-344 (1976).
DNA Cloning: A Practical Approach, vols. I and II, Glover, Ed., IRL Press (1985).
Gene Transfer Vectors for Mammalian Cells, Miller and Calos, Eds., Current Communications in Molecular Biology (1987).
Heneine et al., “No Evidence of Infection with Porcine Endogenous Retrovirus in Recipients of Porcine Islet-Cell Xenograf”,Lancet, vol. 352, No. 9129, pp. 695-699 (1998).
Herring et al., “Monitoring Xenotransplant Recipients for Infection by PERV”,Clin Biochem, vol. 34, No. 1, pp. 23-27 (2001).
Herring et al., “Mapping Full-Length Porcine Endogenous Retroviruses in a Large White Pig”,J Virol, vol. 75, No. 24, pp. 12252-12265 (2001).
Hug et al., “Analysis of Mice Containing a Targeted Deletion of Beta-Globin Locus Control Region 5′ Hypersensitive Site 3”,Mol Cell Biol, vol. 16, No. 6, pp. 2906-2912 (1996).
Introduction to Computational Biology: Maps, Sequences and Genomes, Chapman & Hall, Eds., London (1994).
Jin et al., “Expression of Porcine Endogenous Retrovirus in Peripheral Blood Leukocytes from Ten Different Breeds”,Transpl Infect Dis, vol. 2, No. 1, pp. 11-14 (2000).
Kodo, Gale and Saxon, “Antibody Synthesis by Bone Marrow Cells In Vitro Following Primary and Booster Tetanus Toxoid Immunization in Humans”,J Clin Invest, vol. 73, No. 5, pp. 1377-1384 (1984).
Levy et al., “Liver Allotransplantation after Extracorporeal Hepatic Support with Transgenic (hCD55/hCD59) Porcine Livers: Clinical Results and Lack of Pig-to-Human Transmission of the Porcine Endogenous Retrovirus”,Transplantation, vol. 69, No. 2, pp. 272-280 (2000).
Martin et al., “Expression of Pig Endogenous Retrovirus by Primary Porcine Endothelial Cells and Infection of Human Cells”,Lancet, vol. 352, No. 9129, pp. 692-694 (1998).
Martin et al., “Porcine Endogenous Retrovirus (PERV) was Not Transmitted from Transplanted Porcine Endothelial Cells to Baboons In Vivo”,Transpl Int, vol. 11, No. 4, pp. 247-251 (1998).
Martin et al., “Productive Infection of Primary Human Endothelial Cells by Pig Endogenous Retrovirus (PERV)”,Xenotransplantation, vol. 7, No. 2, pp. 138-142 (2000).
McCreath et al., “Production of Gene-Targeted Sheep by Nuclear Transfer from Cultured Somatic Cells”,Nature, vol. 405, No. 6790, pp. 1066-1069 (1998).
Molecular Cloning: A Laboratory Manual, Second Edition, Sambrook, Fritsch and Maniatis, Eds., Cold Spring Harbor Press, NY (1989).
Myers, Larin and Maniatis, “Detection of Single Base Substitutions by Ribonuclease Cleavage at Mismatches in RNA:DNA Duplexes”,Science, vol. 230, pp. 1242-1246 (1985).
Nucleic Acid Hybridization, Hames and Higgins, Eds., IRL Press (1985).
Oligonucleotide Synthesis. A Practical Approach, Gait, Ed., IRL Press (1984).
Paradis et al., “Search for Cross-Species Transmission of Porcine Endogenous Retrovirus in Patients Treated with Living Pig Tissue”,Science, vol. 285, No. 5431, pp. 1236-1241 (1999).
Patience, Takeuchi and Weiss, “Infection of Human Cells by an Endogenous Retrovirus of Pigs”,Nat Med, vol. 3, No. 3, pp. 282-286 (1997).
Patience et al., “No Evidence of Pig DNA or Retroviral Infection in Patients with Short-Term Extracorporeal Connection to Pig Kidneys”,Lancet, vol. 352, No. 9129, pp. 699-701 (1998).
Pham

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