Pertussis toxoid made by reacting pertussis toxin with the nitra

Details Pertussis toxoid made by reacting pertussis toxin with the nitra Pertussis toxoid made by reacting pertussis toxin with the nitra

1991-09-12

1999-11-23

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4242361, 4242401, 530395, 530405, 530409, A61K 3910, A61K 3902

Patent

active

059895640

ABSTRACT:
A toxoid of pertussis toxin in which the pertussis toxin is modified essentially only at one or more tyrosine residues, as by the use of a nitrating agent such as tetranitromethane or by recombinant DNA techniques; a vaccine including the toxoid; and methods of preparing the toxoid and the vaccine.

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