Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1997-04-23
1999-03-30
Stucker, Jeffrey
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, 435 29, 436518, 4242361, 4242401, 514 2, C12Q 170
Patent
active
058887261
ABSTRACT:
The present invention involves HIV evaluation and AIDS treatment by eliciting lymphocytosis with pertussis toxin in order to reveal the sequestered HIV or SIV in the lymph tissues enabling HIV infection analysis, viral quantification and treatment. The lymphocytosis itself causes an alleviation of the AIDS symptoms and a reduction in the viral load. The present invention could also be used in conjunction with a large variety of adjunct therapies.
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patent: 5667964 (1997-09-01), Ho
Pauza et al, "SIV Transmission Across the Muscosal Barrier", AIDS Research and Human Retroviruses, vol. 10, Supp. 1, 1994, Mary Ann Liebert, Inc. Publishers.
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Pauza et al, "Pathogenesis of SIV.sub.mac351 After Atraumatic Inoculation of the Rectal Mucosa in Rhesus Monkeys", J. Med. Primatol. 22, pp. 154-161, 1993.
Pauza, "Acquired Resistance to Mucosal SIV Infection After low Dose Intrarectal Inoculation: The Roles of Virus Selection and CD8-Mediated T Cell Immunity", Huitieme Colloque Des Cent Gardes, pp. 151-156, 1993.
Pauza, "Transmission of SIV by Intrarectal in Rhesus Monkeys", Septieme Colloque Des Cent Gardes, pp. 69-74, 1992.
Trivedi et al, "Selective Amplification of Simian Immunodeficiency Virus Genotypes After Intratectal Inoculation of Rhesus Monkeys", Journal of Virology, vol. 68, No. 11, pp. 7649-7653, Nov. 1994.
Person et al. "Pertussis Toxin-Induced Lymphocytosis is Associated with Alterations in Thymocyte Subpopulations", Journal of Immunology, vol. 148, No. 5(1992 Mar. 1), pp. 1506-1511.
Stucker Jeffrey
Wisconsin Alumni Research Foundation
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