Perturbed membrane-binding compounds and methods of using...

Details Perturbed membrane-binding compounds and methods of using... Perturbed membrane-binding compounds and methods of using...

2007-09-18

2007-09-18

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

C424S009364, C424S009400

Reexamination Certificate

active

10799586

ABSTRACT:
The present invention relates to compounds that selectively bind to cells undergoing perturbations and alterations of their normal plasma membrane organization, such as cells undergoing apoptosis or activated platelets. The invention further provides methods for utilizing said compounds in medical practice, for diagnostic and therapeutic purposes.

REFERENCES:
patent: 1401579 (1973-09-01), None
patent: WO 02/46147 (2002-06-01), None
Stubbe et al , “Are Carboxylations Involving Biotin Concerted or Nonconcerted?”, The Journal of Biological Chemistry, vol. 255. No. 1, 1980 pp. 236-242.

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