Peroxisome proliferator activated receptor modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S367000, C514S374000, C514S236800, C514S256000, C514S255050, C514S340000, C514S342000, C514S326000, C548S204000, C548S153000, C548S236000, C544S333000, C544S405000, C546S269100, C546S268700, C546S209000

Reexamination Certificate

active

07153878

ABSTRACT:
The present invention is directed to compounds represented by the following structural formula, and pharmaceutically acceptable salts thereof, Formula I. (Formula I); wherein: (a) R5 is selected from the group consisting of (C1–C6)alkyl, (C1–C6)alkenyl, aryl (C0–C4)alkyl, aryloxy(C0–C4)alkyl, arylthio(C0–C4)alkyl, and further wherein when R5 is alkyl, R5 can optionally combine with W to form a 6 membered cycloheteroalkyl ring that is fused with the oxazole or thiazole ring to which the R5 group is attached; (b) R9 is selected from the group consisting of C1–C5alkyl, C1–C5alkenyl, and arylC0–C3alkyl. (c) T1is selected from the group consisting of C and N, (d) W is selected from the group consisting of CH2, C(O)N(R21), N(R21), N(R21)CH2, O, OCH2, S, and SO2; and (e) X is selected from the group consisting of C, CH2C, and CCH2

REFERENCES:
patent: 6787552 (2004-09-01), Sakuma et al.
patent: 0 930 299 (1999-07-01), None
patent: WO 01 00603 (2001-01-01), None
patent: WO 02 18355 (2002-03-01), None
patent: WO 02 062774 (2002-08-01), None
patent: WO 03 072100 (2003-09-01), None

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