Peroxidase-activating oral compositions

Details Peroxidase-activating oral compositions Peroxidase-activating oral compositions

1996-08-15

1999-06-01

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Oxygen or chlorine releasing compound containing

424 48, 424440, 424490, 424613, 106 35, 433215, A61K 968, A61K 720, A61K 3340

Patent

active

059086149

ABSTRACT:
A peroxidase-activating oral care composition, in accordance with an embodiment of the invention, includes a non-enzymatic, water-soluble hydrogen peroxide precursor and a pH-adjusting agent capable of producing a selected pH in an aqueous solution. The composition facilitates the rapid release of hydrogen peroxide and results in the activation of a peroxidase enzyme in an oral cavity A process for manufacturing the oral care composition including obtaining the precursor, dispersing it in a non-hygroscopic material so as to coat or encapsulate it, obtaining and associating the coated or encapsulated particles with a pH-adjusting agent, and formulating the particles into an oral care composition is provided in another embodiment. In addition, a method for activating a peroxidase system in an oral cavity of an animal, including selecting a non-enzymatic water soluble hydrogen peroxide precursor, mixing the precursor with a pH-adjusting agent, and administering the precursor and pH-adjusting agent in a suitable formulation to the oral cavity, is provided in a further embodiment of the invention.

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