Peroral preparation of acid-unstable compound

Details Peroral preparation of acid-unstable compound Peroral preparation of acid-unstable compound

1989-04-04

1991-07-30

Page, Thurman

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424482, 427 3, A61K 936

Patent

active

050358995

ABSTRACT:
A peroral preparation of an acid-unstable compound comprises (1) a core containing the acid-unstable compound, (2) a first layer, coated on the core, comprising a hardly water-soluble, film-forming material and fine particles of a hardly water-soluble substance, suspended in the material, and (3) a second layer, coated on the first layer, of enteric film. The acid-unstable compound is a benzimidazole compound.

REFERENCES:
patent: 4786505 (1988-11-01), Lovgren et al.
patent: 4853230 (1989-08-01), Lovgren et al.

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