Peritoneal dialysis solution containing modified icodextrins

Details Peritoneal dialysis solution containing modified icodextrins Peritoneal dialysis solution containing modified icodextrins

2007-04-24

2007-04-24

Lewis, Patrick (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S054000, C424S078050, C424S078310, C424S085100, C424S085100, C424S177100, C424S180100, C210S647000

Reexamination Certificate

active

10824549

ABSTRACT:
The present invention provides a peritoneal dialysis solution that contains heat stable osmotic agents such as D-glucitols, gluconic acids and alkylglycosides produced the reduction, oxidation or glycosylation of icodextrins respectively. As a result, osmotic agents that are stable under autoclaving or heat sterilization conditions are provided which reduces the amount of bioincompatible materials in the sterilized peritoneal dialysis solutions. Methods of preparing the D-glucitols, gluconic acids and alkylglycosides are disclosed.

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