Peripherally selective dopamine antagonists in the treatment of

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514320, 514324, 514913, A61K 3133, A61K 31445

Patent

active

045017492

ABSTRACT:
Peripherally selective dopamine antagonists are useful in the treatment of ocular hypertension when administered topically to the eye.

REFERENCES:
patent: 4370324 (1983-01-01), Bernstein
patent: 4412999 (1983-11-01), Remy et al.
Langham, "The Intraocular Pressure Response to .alpha. and .beta. Adrenergic Agonists in Normal and Glaucomatous Eyes", International Glaucoma Symposium (France), 1974.
Rosenbaum, "A Controlled Clinical Evaluation of Timolol in the Treatment of Patients with Elevated Intraocular Pressure", Glaucoma, vol. 1(1): 21-24, (1979).
Merck Index, 9th Edition, entry 6018, pp. 801-802, (1976).

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