Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-02-03
1998-06-02
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514309, 514316, 514322, 514323, 514324, 514326, 514329, 546193, A61K 31445, C07D40106
Patent
active
057600589
ABSTRACT:
Peripheral vasodilating agents containing as an active ingredient, a piperidine derivative or pharmaceutically acceptable salt thereof having excellent peripheral vasodilating activity, said piperidine derivative or pharmaceutically acceptable salt thereof being represented by the general formula (1) ##STR1## wherein R, R.sup.1 and R.sup.2 are as defined herein.
REFERENCES:
patent: 3963996 (1976-06-01), Skerlos
patent: 4409228 (1983-10-01), Nisato
patent: 4454130 (1984-06-01), Tominaga et al.
patent: 4455422 (1984-06-01), Banno et al.
patent: 4460593 (1984-07-01), Banno et al.
patent: 4468402 (1984-08-01), Tominaga et al.
patent: 4487772 (1984-12-01), Tominaga et al.
patent: 4567187 (1986-01-01), Banno et al.
patent: 4619932 (1986-10-01), Banno et al.
patent: 4806552 (1989-02-01), Archibald
patent: 4886809 (1989-12-01), Tamada et al.
patent: 4895841 (1990-01-01), Sugimoto et al.
patent: 4902800 (1990-02-01), Skotnicki
patent: 5008274 (1991-04-01), Nishi et al.
patent: 5071856 (1991-12-01), Tamada et al.
patent: 5100901 (1992-03-01), Sugimoto et al.
patent: 5196439 (1993-03-01), Sugimoto
patent: 5574044 (1996-11-01), Thompson
An Improved Method for Reductive Alkylation of Amines Using Titanium(IV) Isopropoxide and Sodium Cyanoborohydride, Ronald J. Mattson et al., J. Org. Chem. 1990, 55, pp. 2552-2554. piperidines, Joan M. Croon et al., J. Pharm. Science, vol. 76, No. 1, Jan. 1987, pp. 32-34.
Tests of a Piperidino Mask for the Protection of Functionalized Carbon Sites in Multistep Syntheses, R. A. Olofson et al., J. Org. Chem. 1984, 49, pp. 2795-2799.
Synthesis of 1-and 3-(1-Substituted 4-Piperidinyl)-1,2,3,4-tetrahydro-2-oxoquinqzolines as Potential Antihypertensive Agents, Haruki Takai et al., Chem. Pharm. Bull, 1985, vol. 33, No. 3, pp. 1116-1128.
Synthesis of (1-Substituted Piperidin-4-yl)-1H-benzimidazoles and (1-Substituted Piperidin-4-yl)-3,d-dihydroquinazolines as Possible Antihypertensive Agents, Hiroyuki Obase et al., H. Heterocyclic Chem. vol. 20, May-Jun. 1983, pp. 565-573.
A Fast N-Substituted .alpha.-Aminonitrile Synthesis, Khuong Mai et al., Synthetic Communications, vol. 15, No. 2., 1985, pp. 157-163.
Cardiotonic Agents. 6. Histamine Analogues as Potential Cardiovascular Selective H.sub.2 Agonists, John W. Lampe et al., J. Med. Chem. 1990, vol. 33, pp. 1688-1697. Sulfur Nucleophiles, K. Avasthi et al., Can. J. Pharm. Sciences, 1981, vol. 16, No. 1, pp. 52-56.
Fujioka Takafumi
Shimizu Hiroshi
Tabusa Fujio
Tanaka Michinori
Teramoto Shuji
Chang Ceila
Otsuka Pharmaceutical Co. Ltd.
LandOfFree
Peripheral vasodilating agent containing piperidine derivative a does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peripheral vasodilating agent containing piperidine derivative a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peripheral vasodilating agent containing piperidine derivative a will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1460206